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NEWS

Tranquillisers Instead of Heroin?
Date: 21/11/2008
Article about the rise of tranquilliser use because of a heroin shortage

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Equivalence

Equivalent doses to 5mg Diazepam(Valium) - half life 20-200 hours

Generic Name

Brand Name

Dosage

Half Life (hours)

Active Metabolite (hrs)

Alprazolam

Xanax

0.5 mg

6-12

 

Bromazepam

Lexotan

6.0 mg

10-20

 

Chlordiazepoxide

Librium

10.0 mg

5-30

36-200

Clobazam

Frisium

5.0 mg

12-60

 

Clorazepate

Tranxene

2.5 mg

 

36-200

Flunitrazepam

Rohypnol

0.5 mg

20-30

36-200

Flurazepam

Dalmane

15.0 mg

 

40-250

Ketazolam

Anxon

6.0 mg

36-200

 

Loprazolam

Dormonoct

0.5 mg

6-12

 

Lorazepam

Ativan

0.5 mg

10-20

 

Lormetazepam

 

0.5 mg

10-12

 

Medazepam

Nobrium

4.0 mg

 

36-200

Nitrazepam

Mogadon

5.0 mg

15-38

 

Oxazepam

Oxanid

15.0 mg

4-15

 

Temazepam

Normison

10.0 mg

8-22

 

Triazolam

Halcion

0.25 mg

2

 

Zaleplon

Sonata

10 mg

1

 

Zolpidem

Stilnoct

10 mg

2

 

Zopiclone

Zimovane

7.5 mg

5-6

 

Notes

All benzodiazepines (and the 'Z' drugs listed) act similarly but also differ, particularly in the length of time they remain in the blood. The dosage required to produce similar effects can vary greatly.

This table shows what dose of other drugs is needed to give roughly the same effect as 5mg of diazepam. This is useful information for people changing to diazepam as an aid to coming off.

Other information in the table is the half life of the substance - a measure of how long it remains active. Some benzos are changed by the human system into another active compound or active metabolite. This usually has a longer half life as shown in the right-hand column. The benzos with short half lives tend to be used as sleeping pills and those with longer half lives as tranquillisers.

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